Game changer for weight loss

wow - are drugs a game changer for weight loss?Another Headline announcing a game changer for weight loss.

Apparently, there are new drugs coming to market, each claiming to solve the obesity crisis.




Each anti-obesity drug is a game changer for weight loss!

Wait a minute. What game are they changing?

Anyone who has ever watched a sporting event knows the supposed” game changers”, called substitutes, are not always guaranteed to make things better.

The obesity battle is not a game.

Our healthcare system finally looked like it was taking overweight seriously.

It needs to!

However, we believe that these game changer drugs are more likely to make things seriously worse, except for creating a big revenue stream for the parties involved.

Lipotrim pharmacy poster - life is not a game

The “diet game” as it was

Historically, the doctors have been helpless without safe and effective drugs to prescribe. Many drugs have come and subsequently gone owing to serious side effects, creating additional morbidity and unfortunately many fatalities before their withdrawal. It is likely that there will never be a drug which will offer safe and effective pharmacological remission of excess weight across the whole population.

Thankfully, pharmacists stepped up and made a difference. For almost 25 years they have been providing and documenting a healthcare monitored weight management programme. Numerous publications have provided the evidence behind this pharmacist led obesity intervention programme.

Participating pharmacists have provided the programme at no cost to the health service. The very modest cost to the overweight person is generally much less expensive than the food and drink it replaces. It has been proven effective and safe, saving many lives. Its weight loss could, for example, safely lower a diabetic patient’s excessively high blood sugar, usually during the first week without the need for medication.

Unfortunately, the health service has been too pre-occupied with prescription medication. Invariably, type 2 diabetics, who were eligible for the pharmacy programme, were left in limbo because their GP was unwilling or unknowledgeable enough to co-operate with pharmacy.

Pharmacies are continuing to do a great job in the face of such resistance.

Changing the “diet game” for the better

Fast forward to the last few years. The NHS is finally recognising that overweight and obesity is more than a cosmetic problem. Obesity has contributed to serious complications with the covid pandemic and is acutely escalating the rate of type 2 diabetes.

The NHS has begun to recognise that more than 200 medical conditions are made worse when the patients are overweight.

The NHS now recognises that the more than 40 million UK adults need a more effective answer than the old “eat less and exercise more” mantra.  They need more than platitudes, like the 5-a-day campaign and diet swaps. Type 2 diabetes alone unnecessarily costs the UK taxpayers £millions every day.

A media campaign encouraged overweight people to get help from their pharmacist, but was really a process to gain more referrals to the NHS’s 12-week weight management programme. This is just the same outdated and weak regurgitation of the same old food pyramid, eat less nonsense.

The NHS is also piloting a low calorie diet GP-based programme even though NHS pharmacies have collected real-life evidence over many years using a very low calorie diet. It is critical to note that all VLCDs are not the same, so....

Why ignore pharmacy experience?

Why ignore the real-life evidence?

They have not got it right, but at least it is a major advance.

At least diabetics will get some attention. Unfortunately, if they only paid more attention to the experienced pharmacists and less to the “experts” the benefits would be much quicker, greater, and more certain.

Spending more time and attention along this path, utilising the published pharmacy data and pharmacy, can seriously change the game for the better.

Changing the diet game for the worse

Recently, so-called game changer drugs have emerged. Interpretation of all the published drug research, shows yet again pharmacotherapy is less effective than proven very low calorie diet interventions.

Take the most recent press release from Lilly, April 28, 2002:

Lilly's tirzepatide delivered up to 22.5% weight loss in adults with obesity or overweight in SURMOUNT-1

Now compare this to just one of our Lipotrim pharmacist's data, from Waistaway, published in MDPI Pharmacy 2020 ( It is also worth noting that this is real-life data and not research data collected under controlled conditions:

The Lipotrim total food replacement programme resulted in up to 58% weight loss of initial weight

Funding such drug therapies will cost the NHS a lot of money, whereas a patient-funded pharmacy service has a zero cost to the NHS. The success of modern day VLCDs over the many decades is indisputable. As seen here, VLCDs offer impressive results which eclipse those of these new so-called game changer drugs for weight loss.

In addition, these drugs are often not pleasant and will violate one or both of the two major mechanisms needed for a drug to really succeed:

1. Reduced appetite.

Numerous gastric side effects may well suppress eating but is that the safe goal? Of course not. Even if there is a real physiological effect on appetite it is not a valid goal.

There is a critical reason why we need to eat.

There are about 50 CHEMICALS that we require to live and be healthy. They are called vitamins and minerals, trace elements, and macronutrients such as amino acids, fatty acids and some carbs. We must have them in proper amounts and we only get them from food.

Eating to get these nutrients is difficult. Otherwise, why would the 60% of the population who are overweight be still told they are not eating enough nutrients? Optimal nutrition is virtually impossible if on a seriously restricted intake of conventional foods.

2. So-called increase in metabolic rate.

Burn more calories!  Drugs, exercise and superfoods. These are all reported to increase our metabolic rate to aid weight loss but will consequently increase body heat.

An overweight person, especially one that has reached or exceeded the obese range does not have the ability to get rid of the extra heat produced.

Fat insulates. The extra heat will increase the body temperature which could even be fatal.  Fortunately, most of the time, protective instincts intervene.

Of course, to lose weight by exercise sounds more realistic but despite considerable traditional rhetoric, requires considerable effort. To lose a single pound of body fat the individual needs a deficit of 3500 calories. Running a mile only uses about 100 calories so you can be a whole pound thinner after a 35-mile run. Not many obese people can manage that, especially coupled with the insulation issue mentioned previously.

The pseudo-science of superfoods simply do not merit the words here.

The real game changer for weight loss will be for the NHS to finally recognise the valuable resource they already have in pharmacy and adopt real very low calorie diets.

To get real change something different MUST be done otherwise we will quickly realise the game changer may cause an embarrassing loss of the game.

Losing the obesity game will cost more lives.

Game changer for weight loss -To get real change something different MUST be done
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